Figure 2
An overview of the nanobody structure model. (a) The nanobody structure model and (b) the same model after ensemble refinement. Chain A is shown in ice blue; chain B is shown in white. The CDR regions are shown in purple–red (CDR1), violet (CDR2) and orange (CDR3). From the ensemble refinement model it is obvious that CDR1 and CDR2 are in a fixed conformation, while CDR3 is more flexible. |