Figure 1
Overall structure of HBD from C. acetobutylicum (CacHBD). The structures are shown as (a) a monomer, (b) a dimer and (c) a hexamer containing three dimers in the asymmetric unit. (a) In the monomeric form the N- and C-terminal domains are colored cyan and magenta, respectively. NAD+ is shown as a gray stick model. In the inset, the Fo − Fc OMIT map contoured at 3σ for NAD+ is represented as a blue mesh; it was calculated by excluding the NAD+ molecule. (b) In the dimeric form one monomer is shown in the same colors as in (a) and the other is shown in yellow. (c) In the hexameric form in the asymmetric unit, the dimers are shown in yellow, green and purple. The top and bottom views are shown from the pseudo-threefold and twofold axis directions, respectively. |