Iterative screen optimization maximizes the efficiency of macromolecular crystallization

Jones, H.G.; Wrapp, D.; Gilman, M.S.A.; Battles, M.B.; Wang, N.; Sacerdote, S.; Chuang, G.-Y.; Kwong, P.D.; McLellan, J.S.

doi:10.1107/S2053230X18017338

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

IUCr IT WDC

home archive editors for authors for readers submit subscribe open access

view article

Figure 3
ISO results in an increase in the number of crystals obtained. The number of conditions that yielded crystals per plate for each protein is plotted on the y axis. Each bar along the x axis represents a crystallization plate, ordered 1–4 from left to right. Plate 1 refers to the initial Sweet16 screen and Plates 2–4 refer to the subsequent protein-specific optimized screens. The left half of each bar graph plots the number of conditions that yielded crystals per plate at Day 5 and the right half of each bar graph shows the number of conditions that yielded crystals per plate at Day 21.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 75| Part 2| February 2019| Pages 123-131

https://doi.org/10.1107/S2053230X18017338

Open

access

Follow Acta Cryst. F

Search IUCr Journals		doi		Advanced search
Author		volume	page