Figure 6
Packing of trypsin molecules with intercalating peptide. Two symmetry-related molecules are shown in purple and yellow; the peptide linking the three molecules is shown in red. In addition, residues of BPTI (green; PDB code 3btd
; Helland et al., 1999) and a synthetic peptide inhibitor (blue; PDB code 1ox1
) are superimposed on the central trypsin (grey), showing that the intercalating density occupies a different location from the peptide substrates. Figure prepared with ICM Pro Version 3.7 (Abagyan et al., 1994). |