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Figure 3
Rigid-body modelling of tetrameric pyruvate oxidase. Top: (1) experimental SAXS curve; (2) computed scattering from the model of POX in the crystal [PDB code 1POW; Muller & Schulz (1993BB44)]; (3) scattering from the model provided by a brute-force method using GLOBSYMM with spatial sampling of 0.1 nm and angular sampling of 20°; (4) scattering from the model provided by a global search uisng SASREF. Bottom: the models of POX (from left to right: crystallographic structure, GLOBSYMM model and SASREF model). Models in the bottom row are rotated counterclockwise by 90° around the x axis.

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