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Figure 4
Arrangements of domains in polypyrimidine tract binding protein. Top: experimental SAXS curves and the fits computed for the full-length PTB and its deletion mutants. The domain structure of the protein is schematically displayed in the left panel of the bottom figure. The right panel of the bottom figure presents a typical model of PTB generated by BUNCH as Cα chains of the NMR structures of individual domains, with colours corresponding to those in the left panel, and linkers shown in blue. Superimposed on the BUNCH model is a low-resolution model provided by the multiphase ab initio program MONSA (semi-transparent beads).

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