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![[Figure 4]](po5031fig4mag.jpg)
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Figure 4
Comparison of neutron and X-ray scattering data with models of human immunoglobulin IgG4 composed of Fab and Fc regions (Rayner et al., 2014  ). (a) Atomistic structures of an extended asymmetric (left) and a compact asymmetric (right) IgG4 model. In these, the Fc region is viewed in a similar orientation. (b), (c) Comparisons of the calculated scattering curves for sphere models generated by SCT from the atomistic models with neutron and X-ray experimental data, respectively. The Q range is depicted from 0.2 to 1.6 nm−1. In both cases, the compact asymmetric model (blue curve: PDB code 4pto) gives good fits to the experimental data, whereas the extended model (red curve) does not. |
![[Figure 4]](po5031fig4.jpg)
 | JOURNAL OF APPLIED CRYSTALLOGRAPHY |
ISSN: 1600-5767
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