Figure 2
A hybrid high-resolution model of the human gamma-secretase derived from cryoEM (PDB code 4uis; Sun et al., 2015) (green Cα traces) and the bead models from the electron-density map (ID EMD-2974.map) superimposed onto it by SUPALM (red spheres) and by SUPCOMB (blue spheres). The right view is rotated counterclockwise by 90° around the vertical axis. |