Figure 5
Analysis of the average structure in modulated PA crystals. (a) Cα trace of profilin:actin with the domains of actin labelled. (b)–(e) 2Fo–Fc electron density (2σ, blue; 3σ, red) of (b) wide-open state, periodic structure at 2.3 Å resolution, and (c) xMod1, (d) xMod2 and (e) gMod3 average modulated structures (main reflections + satellites merged with JANA2006). Regions in the average maps with density that is weaker than in the periodic map (circled in red) are the locations in the structure with multiple positions owing to modulation. |