Orientation matrix calculation for two sets of data collected from separate cubic insulin crystals on ID14-4 at the ESRF. Two supersets of 60 images were collected, one with 0.5° wedges (filled circles) and the other 1.0° wedges (filled squares). For each, five subsets of images were randomly generated for sets varying in length from two to ten images. The supersets, and each subset, were processed using XDS. The angular deviation difference between the orientation matrix for each subset and the appropriate superset was then calculated The average values and corresponding variances are shown.