Figure 3
Changes in mineral characteristics related to age in WT mice. (a) The fraction of orientated bone crystals calculated using the 2D-XRD 002 ring intensity associated with oriented and random crystals for the two-week and four- or five-month-old WT mice. (b) The degree of crystal alignment measured using the change in 002 arc angular breadth. (c) The FWHM measured for oriented and random crystal populations using the 002 and 310 reflections in the 1D-XRD patterns. Error bars show the variation expected in the values based on multiple measurements of different pregnant mouse specimens. (d) Mineral-to-collagen versus carbonate-to-phosphate ratios obtained from individual Raman mapped areas in the three WT mouse specimens at different ages. |