Figure 6
ELLLIP builds a liposome as two nested quasi-ellipsoids corresponding to the inner and outer liposome leaflets. The ellipsoidal shapes can be user specified by defining the lengths of the ellipsoid semi-axes (Aout, Bout and Cout for the outer leaflet, and Ain, Bin and Cin for the inner leaflet). Atomic models of the constituent lipids (grey beads) are placed on angular grids (top right) that define the outer (pink) and inner (blue) leaflets of the liposome. After the grids have been populated with lipids, a randomization step occurs in which the lipid molecules are displaced to account for possible disorder. |