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Figure 4
Optimum photon energy En which minimizes the required number of incident photons per pixel [\bar{n}_{\rm pixel}] (left axis) and the corresponding value of [\bar{n}_{\rm pixel}] (right axis) for imaging copper in silicon (a) and protein in tissue (b). These values were obtained from the calculations of [\bar{n}_{\rm pixel}] shown in Fig. 2[link] as a function of both background material thickness and photon energy, assuming SNR = 5 and δr = 20 nm. Also shown is the energy Eest found by setting μ−1(Eest) of equation (4)[link] equal to the total thickness t of the background material. As discussed in Section 3.1[link], the required illumination per pixel in 2D imaging shown here is approximately the same as the integrated illumination per voxel in 3D imaging.

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