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Figure 2
Plots of the number density of lipid heads (NC3 and PO4), tails (C1A–C4A and C1B–C5B) and water (W) versus displacement from the bilayer's midplane for a planar membrane (solid lines) and highly curved vesicle (dotted lines). The schematic of a curved membrane at the top illustrates how lipid packing responds to curvature: lipid heads (smaller circles) in the inner leaflet are tightly packed, whereas lipid heads in the outer leaflet have a larger hydration shell (larger circles).

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