A capillary-based microfluidic device enables primary high-throughput room-temperature crystallographic screening

Sui, S.; Mulichak, A.; Kulathila, R.; McGee, J.; Filiatreault, D.; Saha, S.; Cohen, A.; Song, J.; Hung, H.; Selway, J.; Kirby, C.; Shrestha, O.K.; Weihofen, W.; Fodor, M.; Xu, M.; Chopra, R.; Perry, S.L.

doi:10.1107/S1600576721004155

Journal of Applied Crystallography Journal of Applied
Crystallography

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Figure 6
F_o–F_c electron density maps for Gal-3, showing the compound density difference resulting from soaking with different concentrations of compound. Each panel reflects representative data from a single crystal soaked at the indicated compound concentration, contoured at 3σ, and the nearby Trp181.

JOURNAL OF
APPLIED
CRYSTALLOGRAPHY

ISSN: 1600-5767

Volume 54| Part 4| August 2021| Pages 1034-1046

https://doi.org/10.1107/S1600576721004155

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