A capillary-based microfluidic device enables primary high-throughput room-temperature crystallographic screening

Sui, S.; Mulichak, A.; Kulathila, R.; McGee, J.; Filiatreault, D.; Saha, S.; Cohen, A.; Song, J.; Hung, H.; Selway, J.; Kirby, C.; Shrestha, O.K.; Weihofen, W.; Fodor, M.; Xu, M.; Chopra, R.; Perry, S.L.

doi:10.1107/S1600576721004155

Journal of Applied Crystallography Journal of Applied
Crystallography

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Figure 8
Overview of the envisioned compound screening workflow and the corresponding timeline based on full automation. From loading compound to resolving structure, use of our microfluidic platform significantly improved the efficiency of the compound-screening process.

JOURNAL OF
APPLIED
CRYSTALLOGRAPHY

ISSN: 1600-5767

Volume 54| Part 4| August 2021| Pages 1034-1046

https://doi.org/10.1107/S1600576721004155

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