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Figure 1
X-ray data from a histological thin section of brain tissue. Scattering data are collected simultaneously on (a) WAXS and (b) SAXS detectors. Red circles in (a) indicate the locations of peaks due to the mica substrate. Scattering from the mica substrate is subtracted and the resulting intensities are circularly averaged and merged in (c) and (d). The scattering at 4.7 Å spacing is typical of cross-β structures, including those made from Aβ or tau. (e) Maps of intensity at 4.7 Å spacing as measured in 4941 scattering patterns in a ROI make it possible to locate lesions (circles).

Journal logoJOURNAL OF
APPLIED
CRYSTALLOGRAPHY
ISSN: 1600-5767
Volume 55| Part 6| December 2022| Pages 1562-1571
https://doi.org/10.1107/S1600576722009955
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