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Figure 5
Comparison of cross-section correlation functions from a solid cylinder, from a model amyloid fibril generated from 5oqv and as calculated from SAXS data from in vitro-assembled Aβ fibrils. At low r, the correlation function of the solid cylinder and the PDB model are indistinguishable since the overall dimensions of the fibril and cylinder are essentially the same. They deviate at larger r due to variation from cylindrical shape at the outer surface of the model fibril. Comparison suggests that the in vitro-assembled fibrils are significantly larger than the model fibril, consistent with previous modeling of the fibril structure (Roig-Solvas & Makowski, 2017BB32).

Journal logoJOURNAL OF
APPLIED
CRYSTALLOGRAPHY
ISSN: 1600-5767
Volume 55| Part 6| December 2022| Pages 1562-1571
https://doi.org/10.1107/S1600576722009955
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