Figure 1
Schematic representation of an example serial crystallography experiment. The X-ray beam illuminates a liquid jet, i.e. a medium loaded with protein crystals. Upon beam–crystal interaction, a diffraction image is captured by the detector. Advancements in detector technology enable data collection rates exceeding 1 kHz, resulting in vast data sets (typically several terabytes). Primary data processing involves identifying images with distinct signals and pinpointing strong reflections through spot finding. Subsequent indexing associates spots with the corresponding Miller indices, gathering the requisite statistics for integration and merging. |