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![[Figure 4]](jo5110fig4mag.jpg)
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Figure 4
Photographs and a schematic drawing of the `upside down in dish' setup. The yellow dye visualizes the protein solution. After sample loading, the chip was placed upside down in the petri dish and the precipitation buffer (blue dye) was added at the bottom of the petri dish at the edge of the chip. (a) Initial deposition of the precipitation buffer. (b) After adding sufficient precipitation buffer, the solution should spread underneath the acrylic frame without entering the microfluidic channel. However, petri dishes are less reliable compared with customized storage chambers and can leak if there is extra stress between the petri-dish wall and the corner of the chip. The top channel shows a case where the precipitation buffer flowed into the protein channel resulting in batch crystallization conditions. |
![[Figure 4]](jo5110fig4.jpg)
 | JOURNAL OF APPLIED CRYSTALLOGRAPHY |
ISSN: 1600-5767
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