Figure 6
Large-volume high-quality crystals of TTR obtained by CD using a 1 mm (L1) capillary loaded with 80 mg mL−1 TTR. (a) The dashed boxes designated 1–5 define the areas of the capillary where mesh scans were carried out. For each section the equivalent mesh scan `heatmap' plot and sample diffraction patterns are shown. (b) Calculated variance for each mesh scan. (c) A magnified view of the two single crystals (sections 4 and 5) that were selected for acquisition of complete data sets with the relative merged statistics using a 1.7 Å cut-off. |