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Figure 8
Schematic illustration of the PEGylated liposomal lipid membrane nanostructures and lipid chain packing with 50 mol% cholesterol incorporation based on the SWAXS data analysis. The effects of the aliphatic chain length and DOX intercalation into the liposome bilayers are illustrated through the ordering and disordering of the lipid head and chain regions of the inner and outer leaflets. It is speculated that the DOX molecules become trapped at the center of the hydro­phobic chain region, with their hydro­philic headgroups (represented by green circles) oriented toward one another. The arrow indicates the normal direction of the membranes and the dashed lines outline the curvatures of the leaflets of the membranes.

Journal logoJOURNAL OF
APPLIED
CRYSTALLOGRAPHY
ISSN: 1600-5767
Volume 58| Part 3| June 2025| Pages 897-908
https://doi.org/10.1107/S1600576725003577
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