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Figure 2
Asymmetric lipid bilayers for antibiotic research using the P1 prototype. Setup for the preparation of asymmetric lipid bilayers via sequential LB (A) and LS (B) depositions; insets show a cartoon of the sequential monolayer transfers. NR data and fits for asymmetric dDPPC/LPS bilayers measured in the two compartments of the cell (labelled L and R) (C), and corresponding SLD profiles (D). Volume fraction distribution of the bilayer components (solid lines) and water (dashed lines) in the two samples with bilayer schematics overlaid (E). Roughness reduced to 2 Å for clarity. Plot with original roughness is shown in Fig. S3. NR data (F) and corresponding SLD profiles (G) after the addition of vancomycin (black) and polymyxin B (red) antibiotics in one of the two compartments.

Journal logoJOURNAL OF
APPLIED
CRYSTALLOGRAPHY
ISSN: 1600-5767
Volume 59| Part 2| April 2026| Pages 369-380
https://doi.org/10.1107/S1600576726000919
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