view article

Figure 3
WcbI binds to coenzyme A. (a) Electron-density map showing the binding of coenzyme A (CoA) to WcbI. WcbI is shown as a cyan cartoon, with CoA as sticks. For clarity, water molecules are not shown. An FoFc OMIT map is shown contoured at 3σ. The bond from CoA to Cys14 is shown. (b) Schematic drawing of the WcbI–CoA interactions. (c) Key WcbI–CoA interactions. WcbI is shown as a cyan cartoon, with interacting side chains as purple sticks. CoA is shown as sticks. Hydrogen-bond distances are shown. Nitrogen, blue; oxygen, red, phosphorus, orange; CoA carbon, yellow; WcbI carbon, purple. (a) and (c) were prepared with the PyMOL Molecular Graphics System (Schrödinger) and (b) was prepared with LigPlot+ (Laskowski & Swindells, 2011BB31).

ISSN: 2052-2525