Figure 1
Left: the X-ray structure of LmNMT (2wsa
) in complex with DDD646 (magenta C atoms) occupying the substrate binding site. The adjacent active site is occupied by myristoyl-CoA (green C atoms). Tyr217 is highlighted in white. Right: the four ligands complexed with LmNMT described in the current paper and also found to occupy the substrate binding pocket. |