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Figure 1
Functional domain structures of human demethylases: human LSD1/KDM1A (UniProtKB: O60341), human LSD2/KDM1B (Q8NB78), human KDM4A/JHDM3A/JMJD2A (O75164), human TET1 (Q8NFU7), human TET2 (Q6N021), human TET3 (K9JJH7), FTO (Q9C0B1) and ALKBH5 (Q6P6C2). SWIRM is Swi3p, Rsc8p and Moira domain, AOD is amine oxidase domain, Tower is tower domain, ZF is zinc-finger domain, JmjN is Jumonji N domain, JmjC is Jumonji C domain, PHD is plant homeodomain, Tudor is Tudor domain, CXXC is CXXC zinc-finger domain, Cys-rich is cysteine-rich domain, DSBH is double-stranded β-helix and CTD is C-terminal domain.

IUCrJ
Volume 1| Part 6| October 2014| Pages 540-549
ISSN: 2052-2525
doi:10.1107/S2052252514020922