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Figure 2
Results of ensemble optimization. (a)–(c) Fits between the calculated scattering curve from the best ensemble (coloured, selected by EOM) and the experimental data (black). (d)–(f) Dmax distributions of the conformers in the pool (black) and the optimized ensembles (coloured). (g) Comparison of the Dmax and (h) of the Rg distributions in the optimized ensembles of the three IgG subclasses. (i) A representative structural model of IgG1 generated by RANCH.

ISSN: 2052-2525