view article

Figure 1
Structure of GR. The receptor (PDB entry 3mnp , Seitz et al., 2010BB53; grey ribbon) is an all-helical protein with a central solvent-excluded ligand-binding cavity and a lateral surface binding site for the co-activator. The steroid ligand and co-activator peptide TIF2 are coloured yellow and dark green, respectively. There are no direct contacts between the two molecules. The sequence of the co-activator peptide visible in this structure is NALLRYLLD.

Volume 2| Part 2| January 2015| Pages 177-187
ISSN: 2052-2525