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Figure 1
Structure of GR. The receptor (PDB entry 3mnp , Seitz et al., 2010 ; grey ribbon) is an all-helical protein with a central solvent-excluded ligand-binding cavity and a lateral surface binding site for the co-activator. The steroid ligand and co-activator peptide TIF2 are coloured yellow and dark green, respectively. There are no direct contacts between the two molecules. The sequence of the co-activator peptide visible in this structure is NALLRYLLD. |
IUCrJ
ISSN: 2052-2525
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