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Figure 1
Schematic diagram showing possible behaviours of surface side chains when two proteins interact. (a) The two proteins are shown in surface representation with their solvent accessible surface side chains depicted as red sticks. (b) Compact interaction, where the side-chain conformations fold inwards as the proteins dock together. (c) Rigid interaction, in which the side-chain conformations hardly alter, in terms of solvent accessibility, from their conformations in (a). (d) Extended interaction, with the side chains stretching out to greet their partners as the proteins approach.

IUCrJ
Volume 2| Part 6| October 2015| Pages 609-610
ISSN: 2052-2525