Figure 5
Examples showing changes in secondary-structural elements (left panel, U; right panel, B). Stretches in the interface are in yellow. (a) Amicyanin (PDB entry 2rac
; Zhu et al., 1998) in complex (PDB entry 2mta
; Chen et al., 1994) with methylamine dehydrogenase exhibits the formation of two antiparallel β-strands (Pro52, Asn54, His56 and Val58 in one, and Lys68, Gly69, Pro70, Met71 and Lys73 in the other) and N-terminal (Arg99) and C-terminal (His91) extension of two other strands. (b) Metalloproteinase inhibitor 1 (PDB entry 1d2b
; Wu et al., 2000) in complex (PDB entry 2j0t
; Iyer et al., 2006) with MMP1 intersitial collagenase displays the formation of a small helix (Glu67, Ser68, Val69 and Cys70) and C-terminal (Lys88) extension of a strand. |