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Figure 6
The structure of the interface formed in human tissue inhibitor of metalloproteinases 2 when it forms a complex with type IV collagenase (PDB entry 1gxd ; Morgunova et al., 2002BB35); the inhibitor is denoted in cyan and the enzyme in violet. Surface representations of the proteins are displayed. The U state (PDB entry 1br9 ; Tuuttila et al., 1998BB51) is not shown here. The interface residues are split into two categories: the residues missing in the unbound structure are in blue and those seen in both the U and B forms are in orange. The missing segment (183–192) is composed of both non-interface residues (shown in red) and interface residues (blue). The missing residues contribute 504 Å2 to the BSA of 1268 Å2 of the inhibitor.

IUCrJ
Volume 2| Part 6| October 2015| Pages 643-652
ISSN: 2052-2525
doi:10.1107/S2052252515015250