Figure 7
The loop (1–12) missing in the U form of neurotrophin-4 (PDB entry 1b98
; Robinson et al., 1999; shown as green cartoon) which is present in the B form (PDB entry 1hcf
; Banfield et al., 2001; cyan) on forming a complex with the BDNF/NT-3 growth factor receptor TrkB-d5 (magenta cartoon). The interface residues (in blue) are interspersed with non-interface residues (in red) in the missing loop. The contribution of the missing residues is 383 Å2 to the BSA of 765 Å2. |