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Figure 3
Hot-spot identification for influenza endonuclease. (a) Results of a crystallographic fragment-screening campaign on influenza endonuclease. Small molecules found are depicted as sticks and the locations that were named are labeled. The active-site metal ions (Mn2+) are shown as purple spheres. (b) Sites where 4-­bromopyrazole was located in endonuclease with labels for subpockets 2 and 3.

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