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Figure 5
Crystal packing in Lili-Mip. (a) The arrangement of molecules in a plane. Each molecule is surrounded by six other molecules. (b) Overall crystal packing showing a sheath within a cylinder arrangement. (c) The ππ stacking interaction between Tyr153 and Tyr142 of two neighbouring molecules. (d) The C-­terminal helix interaction with a groove formed by the loops and β-strand in the opening of the ligand-binding site through a salt bridge between Lys131 and Glu61. (e) The third interacting region between neighbouring molecules through hydrogen bonds between Asn45 and Ser109 as well as Arg14 and Gln32.

Volume 3| Part 4| July 2016| Pages 282-293
ISSN: 2052-2525