Figure 2
Stick representation of MZM (green) bound in the active site of hCA II (yellow). 2Fo − Fc X-ray (orange mesh) and neutron (blue mesh) maps are contoured at 1.2σ. The zinc ion is represented by a magenta sphere and hydrogen bonds are depicted as red dashes. Unexchanged nonpolar H and exchanged polar D atoms are colored black and white, respectively. |