Figure 5
Conserved junction structure, interactions and orientation (`open' form). (a) Global view of the junction superposition, highlighting its main conserved structural features. Ala shows the mean position of the unusual alanine in EhCRT. (b) Junction interaction details in TcCRT. (c) Junction interaction details in EhCRT, open conformation. (d) Junction interaction details in HsCRT D71K. Colour code: the junction is shown in dark blue, the truncated P domain in magenta, the linker in orange, TcCRT in cyan, EhCRT in green, HsCRT D71K in black and MmCRT (PDB entry 3rg0) in grey in (a). |