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Figure 3
In-cell protein folding thermodynamics and quinary interactions. (a) Free energies of protein–cytosol interaction calculated for GB1 mutants with different net charges. (b) The quinary interactions calculated for each residue are larger for a charge-changing mutation (D40K, bottom) than for a neutral mutation (I6L, top). Adapted from Monteith et al. (2015BB42).

IUCrJ
Volume 4| Part 2| March 2017| Pages 108-118
ISSN: 2052-2525
https://doi.org/10.1107/S2052252516020625