view article
Figure 4
Both functional and nonspecific interactions occur in the human cytoplasm. (a) Mutations are introduced on the surface of human Pfn1; the mutated residues are colour-coded following the type of functional interaction that is abolished: actin (A, red), phosphoinositides (I, blue), poly-L-proline (P, green). (b) In-cell NMR spectrum of Pfn1 `full' (AIP) mutant in human cells. (c, d) Plots of normalized NMR signal intensity for each Pfn1 mutant in human cells (c) and in bacteria (d). Adapted from Barbieri et al. (2015BB8).

IUCrJ
Volume 4| Part 2| March 2017| Pages 108-118
ISSN: 2052-2525
https://doi.org/10.1107/S2052252516020625