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Figure 1
Subunit of BeSAHase in the closed conformation complexed with 2′-­deoxyadenosine. The domains are colour-coded as follows: blue, substrate-binding domain; salmon, cofactor-binding domain; sand, C-­terminal dimerization domain. The interdomain hinge regions are highlighted in orange (Asn222–Leu233) and green (His392–Val396). The grey triangle highlights the active-site access channel. The molecules of NAD+ (pink) and 2′-deoxyadeosine (grey) are shown in space-filling representation.

IUCrJ
Volume 4| Part 3| May 2017| Pages 271-282
ISSN: 2052-2525
https://doi.org/10.1107/S2052252517002433