Figure 3
Sections tangential to the tube axis spanning the outer phospholipid headgroup region of the lipid bilayer. Low-density patches are present in the space between the δ subunits of neighbouring receptors (see, for example, the box in the third panel) and at the M1/M4 lipid–helix interface of the remaining four subunits (arrows). Inset: enlargement of the boxed dimer of receptors and the central low-density microdomain, identifying individual subunits and the M1 (orange) and M4 (green) helices of δ. The panels are at 2.7 Å intervals from the outermost side (left) to the innermost side of the headgroup region. Inverted contrast. |