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Figure 3
Designing renin inhibitors in the 1980s based on models of renin (Blundell et al., 1983BB16). This was achieved using interactive graphics, maintaining the hydrogen bonds and filling the specificity pockets.

IUCrJ
Volume 4| Part 4| July 2017| Pages 308-321
ISSN: 2052-2525
https://doi.org/10.1107/S2052252517009241