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Figure 3
The Rfree after refinement using REFMAC5 for both summation integration and profile-fitting integration using both the default background algorithm assuming a flat background model and the global background-model algorithm. In all cases, the global background model results in an improvement in the Rfree factors from refinement. Using profile fitting (prf) instead of summation (sum) also results in an improvement in Rfree in each case.

IUCrJ
Volume 4| Part 5| September 2017| Pages 626-638
ISSN: 2052-2525
https://doi.org/10.1107/S2052252517010259