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Figure 3
Approaches to study polydisperse systems using SAXS. The polydispersity problem of complex dynamic systems can be solved either by using advanced computational methods or experimental approaches. Scattering profiles of mixtures are linear combinations of component scattering contributions. SVD or PCA decomposition of a measured scattering profile can provide a scattering basis set. In case the scattering profiles of components can be obtained separately by measurements or computed based on structural models, their volume fractions and structural models can be obtained. Conformational polydispersity can be described in terms of Rg and Dmax distributions and using a set of representative structures.

IUCrJ
Volume 4| Part 5| September 2017| Pages 518-528
ISSN: 2052-2525
https://doi.org/10.1107/S2052252517008740