Figure 1
Representative semi-log plot of the integrated intensity in diffraction peaks versus dose at several dose rates, acquired from a single, fixed-orientation lysozyme crystal at 300 K; Supplementary Fig. S5 shows 260 K data. Solid lines are single-parameter fits at the highest and lowest dose rates based on the model described here; dashed lines indicate the initial exponential trend. The intersection of the horizontal dashed black line with each dose curve determines the half-dose D1/2. Doses and dose rates in all figures are averages within the area of the FWHM of the Gaussian beam. |