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Figure 4
Positional determination of nanomaterials in the nuclear region. The exact three-dimensional distribution of [Gd@C82(OH)22]n in the nuclear region distinguished by sectioning in two orthogonal directions, where the z direction is the beam direction. (a) Successive slices along the z direction. The change in the linear absorption coefficient was used to determine the exact position of the nanomaterials, and lysosomes containing nanoparticles stick together and remain on the surface of the nucleus. The interfaces of the nucleus and vacuoles with nanomaterials are shown by black arrows. (b) Slices along the x direction at five positions (I, II, III, IV and V), as shown in (a). In I, II and V cracks are obvious (red arrows), indicating that the nanomaterials are located on the surface of the nucleus (scale bar 1.0 µm).

IUCrJ
Volume 5| Part 2| March 2018| Pages 141-149
ISSN: 2052-2525
https://doi.org/10.1107/S2052252517017912