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Figure 4
Global comparison between cryo-EM-derived and X-ray-derived SCR0911-bound structures. (a) The cryo-EM and X-ray bc1–SCR0911 structures have been overlaid and the crystal structure is coloured according to the calculated Cα r.m.s.d. value (low coloured cyan and high coloured maroon). The main difference (r.m.s.d. of >2 Å) occurs for the Rieske domain (in the black square), which is known to be mobile during the catalytic cycle. (b) An overlay of the Rieske domains in the cryo-EM-derived (cyan) and X-ray-derived (grey) bc1–SCR0911 structures. (c) The cryo-EM-derived map for the bc1–SCR0911 structure with the Rieske domain fitted shown in the same orientation as in (a) and (b).

Volume 5| Part 2| March 2018| Pages 200-210
ISSN: 2052-2525