view article
Figure 1
Crystal structure of α5NC1homo. (a) Cartoon representation of the crystal structure of recombinant α5NC1 formed by a hexamer composed of two trimers. Each trimer contains three subunits of α5NC1 coloured magenta/orange, cyan/pink and blue/yellow. (b) Cartoon representation of a subunit with a schematic representation of the N-subdomain (green) and C-subdomain (magenta) folds. The N-subdomain consists of β-sheets I (β1, β2, β5 and β10) and II (β3, β4, β6′, β7′, β8 and β9), while the C-subdomain consists of β-sheets I′ (β1′, β2′, β5′ and β10′) and II′ (β3′, β4′, β6, β7, β8′ and β9′). The scheme highlights the fact that β6 and β7 from another protomer (coloured blue) are swapped between the NC1 monomers, whereas β6′ and β7′ (coloured magenta) are swapped from the C-subdomain into the N-subdomain of the same subunit.

IUCrJ
Volume 5| Part 6| November 2018| Pages 765-779
ISSN: 2052-2525
https://doi.org/10.1107/S2052252518012459