Figure 5
(a) Possible orientation of the CH domain in the asymmetric unit. We inferred that the interaction between the FMO and CH domains of human MICAL3 occurs in the A position. Straight lines indicate the shortest distance from the C-terminus of the FMO domain to the N-terminus of the CH domain. (b) Backflip of the CH domain of human MICAL3. Green and red indicate the CH domain and actin-binding helix of human MICAL3, respectively; black and cyan indicate the CH domain and actin-binding helix of mouse MICAL1, respectively. The green arrow indicates the direction from the N-terminus to the C-terminus of the human MICAL3 CH domain; the black arrow indicates the same direction for mouse MICAL1. |