Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals

Wolff, A.M.; Young, I.D.; Sierra, R.G.; Brewster, A.S.; Martynowycz, M.W.; Nango, E.; Sugahara, M.; Nakane, T.; Ito, K.; Aquila, A.; Bhowmick, A.; Biel, J.T.; Carbajo, S.; Cohen, A.E.; Cortez, S.; Gonzalez, A.; Hino, T.; Im, D.; Koralek, J.D.; Kubo, M.; Lazarou, T.S.; Nomura, T.; Owada, S.; Samelson, A.J.; Tanaka, T.; Tanaka, R.; Thompson, E.M.; van den Bedem, H.; Woldeyes, R.A.; Yumoto, F.; Zhao, W.; Tono, K.; Boutet, S.; Iwata, S.; Gonen, T.; Sauter, N.K.; Fraser, J.S.; Thompson, M.C.

doi:10.1107/S205225252000072X

Figure 2
Images of microcrystals formed in batch with constant stirring. As the stir rate increased, the average size of the crystals decreased and the density of the slurry increased. This was confirmed by assessing the crystal density using a hemocytometer.

IUCrJ

Volume 7| Part 2| March 2020| Pages 306-323

ISSN: 2052-2525

https://doi.org/10.1107/S205225252000072X

BIOLOGY | MEDICINE

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