Figure 3
The overall structure of ALSV NS3-Hel. (a) Ribbon model of the crystal structure of ALSV NS3-Hel with annotated secondary-structure elements. Three domains, D1, D2 and D3, are indicated. Unless specified otherwise, all illustrations of the ALSV NS-Hel structure in this paper have the same orientation. (b) Ribbon model of the ALSV NS3-Hel structure with the conserved motifs highlighted using the indicated color codes. (c) Superimposition of the crystal structures of ALSV NS3-Hel and ZIKV NS3-Hel (PDB entry 5jmt; Tian, Ji, Yang, Xie et al., 2016). Right: the same model rotated around the vertical axis by 90°. |